Tissue Regeneration and Limb Preservation 2022 Winners
grant support from
2022 Peter Sheehan Young Innovator Award
On June 24, 2022, we recognized and celebrated the achievements of five exceptional scientists for their groundbreaking research in Tissue Regeneration and Limb Preservation.
The selection of these five winners was based on the following criteria:
The organization of their presentation
Innovation demonstrated in their research
Feasibility of medical translation to the clinical wound healing field
Research potential for industry advancement.
Explore more about each presentation and gain insights by listening to the compelling discussions that unfolded during the award ceremony.
Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing
Scarring is a fibroproliferative disorder that can occur post-operatively resulting in significant functional and esthetic morbidity. Diabetic wounds display poor wound healing and chronic refractory wounds can result in hypertrophic scars. The mechanical ...
Topical treatment with exosomes in bioinspired protein hydrogel reintroduces innate immune response in diabetic wound model
We successfully used cultured human bone marrow multipotent stromal cells and their secreted nanoscale exosomes to accelerate wound closure in diabetic animal models of delayed healing. However, to translate this tissue engineering approach clinically, we...
Digital frailty screening to triage non-healing and complex wounds
Multidisciplinary diabetic foot and wound clinics are recommended to minimize limb amputation risk. However, these centers get easily overloaded when inundated with critically ill patients. Smart referral tools are required to reduce the burden of these c...
Tailored nanofibers with calreticulin for tissue regeneration of diabetic wounds
Diabetic foot ulcers (DFUs) present a substantial healthcare burden. Apart from inert wound dressings, two main categories of diabetic wound care products exist on the US market: non-structural (i.e., topical delivery of biomolecules only) and structural ...
Interleukin-17 governs hypoxic adaptation during wound healing
The prevalence of type 2 diabetes is projected to increase to ~450 million people by 2030. Non-healing foot ulcers affect an estimated 4-10% of diabetic individuals and are a leading cause of non-traumatic amputations. Despite the devastating consequences...
