Drs. Rivkah Isseroff and Min Zhao from UCDavis, along with project leader Marco Rolandi and colleagues, are reporting exciting progress on their Defense Advanced Research Projects Agency (DARPA) project. Their collaborative efforts involve actively developing and testing intelligent bandages to cut healing time in half. This innovative approach includes the delivery of ion channel modulators and electric currents to precisely promote wound healing. The team’s overarching objective is closed-loop control and precision temporal-spatial modulation.
ADRIANA C. PANAYI, MD, PHD: After earning our Peter Sheehan Young Innovator Award in Tissue Regeneration and Limb Preservation in 2022 (listen to her presentation here), Dr. Panayi now at BG Klinik Ludwigshafen, University of Heidelberg has established a STATE-OF-THE-ART LAB dedicated to chronic wound healing.
Additionally, she has become a member of the Board of the European Tissue Repair Society, and in Spring 2024, she is scheduled to present at the Wound Healing Society Congress.
-- An update on titles and awards: Dr. Panayi was honored with the Paul Ehrlich Rising Star in Wound Healing Award by the Wound Healing Foundation.
RAM KINKER MISHRA, PHD: His earlier work titled 'The application of digital frailty screening to triage nonhealing and complex wounds', earned him our Peter Sheehan Young Innovator Award in Tissue Regeneration and Limb Preservation in 2022 (listen to his presentation here). This work has been published in the Journal of Diabetes Science and Technology.
IN THIS STUDY, Dr. Mishra and his team showcased how digital biomarkers of frailty, assessed in a quick 20-second test, could serve as a practical tool for prioritizing patients with nonhealing diabetic foot ulcers (DFU).
The identification of patients exhibiting signs of exhaustion frailty phenotype may indicate a heightened risk of presenting with more severe wounds. THE FINDINGS can promote healthcare equity, alleviate scheduling delays, and reduce the risk of lower extremity amputations with underserved populations.
SANGEETHA VADAKKE-MADATHIL: From Mount Sinai School of Medicine, Dr. Vadakke-Madathil received the Peter Sheehan Young Innovator Award in 2018 (see details of her presentation here) and is currently immersed in research focused on human placental-derived CDX2 cells and their pivotal role in cardiovascular regeneration.
THIS RESEARCH has progressed to the translational stage, involving the utilization of approximately 106 human placental samples for their cell culture-based experiments and other related studies.
In the UPCOMING PHASES, Dr. Vadakke-Madathil plans to conduct cell transplantation experiments in humanized small animal models to delve into the intricacies of cardiac repair, followed by investigations in larger animal models.
-- An update on titles and awards: Dr. Vadakke-Madathil and her team were featured in the Smithsonian magazine in 2021, and in 2022, they received an i3 Genesis award from Mount Sinai Innovation Partners.
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🚀 Revolutionary Skin Regeneration Breakthrough Unveiled at Wake Forest Institute
-- Brief Overview: Wake Forest Institute for Regenerative Medicine achieves a major leap in skin regeneration using revolutionary bioprinting technology, promising enhanced wound healing for burn victims and those with skin disorders.
· Key Findings:
Conclusion: WFIRM's breakthrough offers transformative possibilities in regenerative medicine, paving the way for advanced treatments in skin-related conditions."
🧲 NUS Innovation: Magnetic Gel Boosts Diabetic Wound Healing 3 Times Faster Than Standard Care
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🩸 UNIST Breakthrough: Harnessing Blood Power for Scarless Wound Healing
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🦠 RMIT and University of South Australia Unveil Breakthrough Nano-Thin Material Combatting Drug-Resistant Bacteria
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🔬 CLINICAL TRIALS
🏥 FDA 510(k) CLEARANCES
--- Maxiocel Chitosan Wound Dressing by Advamedica Inc.
FDA cleared August 2023
Indication for use: The Maxiocel Chitosan Wound Dressing is indicated for the management of moderately to heavily exuding chronic and acute wounds and to provide a barrier against bacterial penetration.
--- 091 Balloon Guide Catheter by EOSolutions, Corp.
FDA cleared October 2023
Indication for use: The 091 Balloon Guide Catheter is indicated for use in facilitating the insertion and guidance of intravascular catheters into a selected blood vessel in the peripheral and neuro vascular systems. The balloon provides temporary vascular occlusion during these and other angiographic procedures. The Balloon Guide Catheter is also indicated for use as a conduit for Retrieval devices.
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